00:402 years ago24 views

Immortalized human cells to model atrial fibrillation in vitro

Niels Harlaar is a PhD Candidate at the Laboratory of Experimental Cardiology at the Leiden University Medical Center. Here, under the supervison of prof. dr. D.A. Pijnappels and dr. A.A.F. de Vries, he focusses on the conditional immortalization of human atrial cardiomyocytes for (among many other applications) in vitro modelling of atrial fibrillation. He has successfully generated, characterized and applied this technique of these conditionally immortalized human atrial myocyte lines to model atrial fibrillation in vitro.

Niels won the Hugo van Poelgeest prize 2022 for excellent research to replace animal testing.

Click here for more information on the Laboratory of Experimental Cardiology.